Методичні рекомендації ESPEN щодо клінічного харчування у відділенні інтенсивної терапії

Автор(и)

  • Pierre Singer
  • Annika Reintam Blaser
  • Mette M. Berger
  • Waleed Alhazzani
  • Philip C. Calder
  • Michael P. Casaer
  • Michael Hiesmayr
  • Konstantin Mayer
  • Juan Carlos Montejo
  • Claude Pichard
  • Jean-Charles Preiser
  • Arthur R.H. van Zanten
  • Simon Oczkowski
  • Wojciech Szczeklik
  • Stephan C. Bischoff

DOI:

https://doi.org/10.25284/2519-2078.2(87).2019.171009

Ключові слова:

Інтенсивна терапія, харчування, ентеральне, парентеральне, методичні рекомендації, ESPEN

Анотація

Згідно з новими стандартними операційними процедурами ESPEN були оновлені попередні рекомендації щодо забезпечення найкращого медичного нутритивного забезпечення для критично хворих пацієнтів. Дані рекомендації визначають, хто є пацієнтами в групі ризику, як оцінити нутритивний статус пацієнта ВІТ, як визначити кількість енергії, яку необхідно забезпечити, який обрати шлях для нутритивного забезпечення та як адаптувати пацієнта у відповідності до різних клінічних умов. Також описано, коли слід розпочати і як просуватися в управлінні процесом адекватного забезпечення поживними речовинами. Запропоновано найкраще визначення кількості та походження вуглеводів, жирів і білків. Особлива увага приділяється глутаміну і омега-3 жирним кислотам. Обговорюються конкретні стани, що часто спостерігаються в інтенсивній терапії, такі як пацієнти з дисфагією, виснажені пацієнти, пацієнти з множинними травмами, абдомінальна хірургія, сепсис і ожиріння, з метою ознайомлення практикуючого лікаря з найкращою доказовою терапією. Моніторинг цієї нутритивної терапії обговорюється в окремому документі.

Посилання

Kreymann K.G., Berger M.M., Deutz D.E., Hiesmayr M., Jolliet P., Kazandjiev G., et al. ESPEN guidelines on enteral nutrition: intensive care. Clin. Nutr. 2006;25:210-23.
|

Singer P., Berger M.M., Van den Berghe G., Biolo G., Calder P., Forbes A., et al. ESPEN guidelines on Parenteral Nutrition: intensive care. Clin Nutr 2009;33: 246-51.
|

Bischoff S.C., Singer P., Koller M., Barazzoni R., Cederholm T., Van Gossum A. Standard operating procedures for the ESPEN guidelines and consensus papers. Clin. Nutr. 2015;34:1043-51.
|

Singer P., Weinberger H., Tadmor B. Which nutrition regimen for the co-morbid complex intensive care unit patient? World Rev Nutr Diet 2013;105: 169-74.

Wischmeyer P.E. Tailoring nutrition therapy to illness and recovery. Crit Care 2017;21(Suppl. 3):316.
|

Bendavid I., Singer P., Theilla M., Themessl-Huber M., Sulz I., Mouhiedienne M., et al. Nutrition Day ICU: a 7 year worldwide prevalence study of nutrition practice in intensive care. Clin. Nutr. 2017;36:1122-9.

National Institute for Health and Clinical Excellence. The guidelines manual. London: National institute for Health and Clinical Excellence; November 2012. www.nice.org.uk.

Mantel N., Haenzel W. Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer. Inst. 1959;22:19-748.
|

Higgins J.P., Thompson S.G., Deeks J.J., Altman D.Gl. Measuring inconsistency in meta-analysis. BMJ 2003;327: 557-60.
|

Review manager (RevMan) [computer program]. Version [6.6]. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration; 2014.

http://gdt.guidelinedevelopment.org.

Zapletal E., Lemaitre D., Menard J., Degoulet P. The number needed to treat: a clinically useful normogram in its proper context. BMJ 1996;312:426-9.
|

Cederholm T., Barazzoni R., Austin P., Ballmer P., Biolo G., Bischoff S.C., et al. ESPEN guidelines on denitions and terminology of clinical nutrition. Clin. Nutr. 2016;34: 334-40.

Peterson C.M., Thomas D.M., Blackburn G.L., Heymseld S.B. Universal equation for estimating ideal body weight and body weight at any BMI. Am. J. Clin. Nutr. 2016;103:1197-203.

Reintam Blaser A., Starkopf J., Alhazzani W., Berger M.M., Casaer M.P., Deane A.M., et al. Early enteral nutrition in critically ill patients: ESCIM clinical practice guidelines. Intensive Care Med. 2017;43:380-98.
|

Casaer M.P., Mesotten D., Hermans G., Wouters P.J., Schetz M., Meyfroidt G., et al. Early versus late parenteral nutrition in critically ill adults. N. Engl. J. Med 2011;365:506-17.
|

National Institute of Clinical Excellence. Nutritional support in adults: oral, enteral and parenteral nutrition. London, UK: NICE; 2006. NICE guidelines CG32.

McDermid R.C., Stelfox H.T., Bagshaw S.M. Frailty in the critically ill: a novel concept. Crit Care 2011;15:301.
|

Fried L.P., Tangen Cm., Walston J., Newman A.B., Hisch C., Gottdiener J., et al. Frailty in older adults: evidence for a phenotype. J. Gerontol. A Biol. Sci. Med. Sci 2001;56:M146-56.
|

Cederholm T., Bosaeus I., Barazzoni R., Bauer J., Van Gossum A., Klek S., et al. Diagnostic criteria for malnutritionan ESPEN consensus statement. Clin. Nutr. 2015;34:335-40.
|

Mogensen K.M., Robinson M.K., Casey J.D., Gunasekera N.S., Moromizato T., Rawn J.D., et al. Nutritional status and mortality in the critically ill. Crit. Care Med. 2015;43:2605-15.
|

Detsky A.S., Baker J.P., Mendelson R.A., Wolman S.L., Wesson D.E., Jeejeebhoy K.N. Evaluating the accuracy of nutritional assessment techniques applied to hospitalized patients: methodology and comparisons. J. Parenter Enteral Nutr. 1984;8:153-9.
|

Sheean P.M., Peterson S.J., Chen Y., Liu D., Lateef O., Braunschweig C.A. Utilizing multiple methods to classify malnutrition among elderly patients admitted to the medical and surgical intensive care units (ICU). Clin. Nutr. 2013;32:752-7.
|

Cederholm T., Jensen G.L., Correia I., Gonzales M.C., Fukushima R., Higashiguchi T., et al. The GLIM criteria for the diagnosis of malnutrition-a consensus report from the global clinical nutrition community. Clin. Nutr. 2018 (in press). Coltman A., Peterson S., Roehl K., Roosevelt H., Sowa D. Use of 3 tools to assess nutrition risk in the intensive care unit. J Parenter Enteral Nutr 2015;39: 28-33.
|

Rockwood K., Song X., MacKnight C., Bergman H., Hogan D.B., McDowell I., et al. A global clinical measure of tness and frailty in elderly people. CMAJ 2015;173:489-95.
|

Studenski S.A., Peters K.W., Alley D.E., Cawthon P.M., McLean R.R., Harris T.B., et al. The FNIH sarcopenia project: rationale, study description, conference recommendations, and nal estimates. J. Gerontol. A Biol. Sci. Med. Sci. 2014;69: 547-58.

Wischmeyer P., San-Millan I. Winning the war against ICU-acquired weakness: new innovations in nutrition and exercise physiology. Crit Care 2015;19:S6.
|

Looijaard W.G., Dekker I.M., Stapel S.N., Girbes A.R., Twisk J.W., Oudemans-van Straaten H.M., et al. Skeletal muscle quality as assessed by CT-derived skeletal muscle density is associated with 6-month mortality in mechanically ventilated critically ill patients. Crit Care 2016;20:386.
|

Thibault R., Makhlouf A.M., Mulliez A., Gonzalez M.C., Kekstas G., Kupczyk K., et al. Fat-free mass at admission predicts 28-day mortality in intensive care unit patients: the international prospective observational study PHASE ANGLE PROJECT. Intensive Care Med 2016;42:1445-53.
|

Puthucheary Z.A., Rawal J., McPhail M., McPhail M., Connolly B., Ratnayake G., et al. Acute skeletal muscle wasting in critical illness. JAMA 2013;310:1591-600.
|

Lad U.P., Satyanarayana P., Shisode-Lad S., Siri C.C., Kumari N.R. A study of the correlation between the body mass index, the body fat percentage, the handgrip strength and the handgrip endurance in underweight, normal weight and overweight adolescents. J. Clin. Diagn. Res. 2013;7:51-4.
|

Fan E., Ciesla N.D., Truong A.D., Bhoopathi V., Zeger S.L., Needham D.M. Inter rate reliability of manual muscle strength testing in ICU survivors and simulated patients. Intensive Care Med. 2010;36:1038-43.
| |

Savalle M., Gillaizeau F., Maruani G., Puymirat E., Bellenfant F., Houillier P., et al. Assessment of body cell mass at bedside in critically ill patients. Am. J. Physiol. Endocrinol. Metabol. 2012;303:E389-96.
| |

Kuchnia A., Earthman C., Teigen L., Cole A., Mourtzakis M., Paris M., et al. Evaluation of bioelectrical impedance analysis in critically ill patients: results of a multicenter prospective study. J. Parenter. Enteral. Nutr. 2017;41:1131-8.
| |

Ringaitiene D., Gineityte D., Vicka V., Zvirblis T., Norkiene I., Sipylaite J., et al. Malnutrition assessed by phase angle determines outcomes in low-risk cardiac surgery patients. Clin Nutr 2016;35:1328-32.
| |

da Silva T.K., Berbigier M.C., Rubin B. de A., Moraes R.B., Corrêa Souza G., Schweigert Perry I.D.. Phase angle as a prognostic marker in patients with critical illness. Nutr Clin Pract 2015;30:261-5
| |

Lee Y., Kwon O., Shin C.S., Lee S.M. Use of bioelectrical impedance analysis for the assessment of nutritional status in critically ill patients. Clin Nutr Res 2015;4:32-40.

Reis de Lima e Silva R., Porto Sabino Pinho C., Galvão Rodrigues I., Gildo de Moura Monteiro Jenior J.. Phase angle as an indicator of nutritional status and prognosis in critically ill patients. Nutr. Hosp. 2014;31.1278-1278.
| |

Braunschweig C.A., Sheean P.M., Peterson S.J., Gomez-Perez S., Freels S., Lateef O., et al. Exploitation of diagnostic computed tomography scans to assess the impact of nutrition support on body composition changes in respiratory failure patients. J. Parenter Enteral Nutr 2014;38:880-5.
| |

Taylor B.E., McClave S.A., Martindale R.G., Warren M.M., Johnson DR, Braunschweig C, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: society of critical care medicine (SCCM) and American society for parenteral and enteral nutrition (A.S.P.E.N.). Crit. Care Med. 2016;44:390-438.
| |

Kondrup J., Rasmussen H.H., Hamberg O., Stanga Z. Nutritional risk screening (NRS 2002); a new method based on analysis of controlled clinical trials. Clin. Nutr. 2003;22:321-36.

Heyland D.K., Dhaliwal R., Jiang X., Day A.G. Identifying critically ill patients who benet the most from nutrition therapy: the development and initial validation of a novel risk assessment tool. Crit Care 2011;15:R268.
| |

Elia M. The ‘MUST’ report. Nutritional screening for adults: a multidisciplinary responsibility. Development and use of the ‘Malnutrition Universal Screening Tool’ (MUST) for adults. Redditch, UK: BAPEN; 2003.

Arabi Y.M., Aldawood A.S., Al-Dorzi H.M., Tamim H.M., Haddad S.H., Jones G., et al. PermiT trial group: permissive underfeeding or standard enteral feeding in high and low nutritional risk critically ill adults: post-hoc analysis of the PermiT trial. Am. J. Respir. Crit. Care Med. 2017;195:652-62.
|

Arabi Y.M., Preiser J.C. A critical view on primary and secondary outcome measures in nutrition trials. Intensive Care Med. 2017;43:1875-7.
| |

Lew C.C., Yandell R., Fraser R.J., Chua A.P., Chong M.F., Miller M. Association between malnutrition and clinical outcomes in the intensive care unit: a systematic review. J. Parenter. Enteral. Nutr. 2017;41:744-58.
| |

Canales C., Elsayes A., Yeh D.D., Belcher D., Nakayama A., McCarthy C.M., et al. Nutrition Risk in critically ill versus the Nutritional Risk Screening 2002: are they comparable for assessing risk of malnutrition in critically ill patients? J Parenter Enteral Nutr 2018 May 30. https://doi.org/10.1002/jpen.1181 [Epud Ahead of print].
| |

Jolliet P., Pichard C., Biolo G., Chiolero R., Grimble G., Leverve X., etal. Enteral nutrition in intensive care patients: a practical approach. Clin Nutr 1999;18:47-56.
| |

Minard G., Kudsk K.A., Melton S., Patton J.H., Tolley E.A. Early versus delayed feeding with an immune-enhancing diet in patients with severe head injuries. J. Parenter. Enteral. Nutr. 2000;24:145-9.
| |

Peck M.D., Kessler M., Cairns B.A., Chang Y.H., Ivanova A., Schooler W. Early enteral nutrition does not decrease hypermetabolism associated with burn injury. J. Trauma 2004;57:1143-8.

Nguyen N.Q., Fraser R.J., Bryant L.K., Burgstad C., Chapman M.J., Bellon M., et al. The impact of delaying enteral feeding on gastric emptying, plasma cholecystokinin, and peptide YY concentrations in critically ill patients. Crit Care Med 2008;36:1469-74.
|

Moses V., Mahendri N.V., John G., Peter J.V., Ganesh A. Early hypocaloric enteral nutritional supplementation in acute organophosphate poisoning–a prospective randomized trial. Clin Toxicol 2009;47:419-24.
|

Chourdakis M., Kraus M.M., Tzellos T., Sardeli C., Peftoulidou M., Vassilakos D., et al. Effect of early compared with delayed enteral nutrition on endocrine function in patients with traumatic brain injury: an open-labeled randomized trial. J. Parenter. Enteral. Nutr. 2012;36:108-1016.
|

Pupelis G., Selga G., Austrums E., Kaminski A. Jejunal feeding, even when instituted late, improves outcomes in patients with severe pancreatitis and peritonitis. Nutrition 2001;17:91-4.
|

Malhotra A., Mathur A.K., Gupta S. Early enteral nutrition after surgical treatment of gut perforations: a prospective randomized study. J. Postgrad. Med. 2004;50:102-6.
|

Kaur N., Gupta M.K., Minocha V.R. Early enteral feeding by nasoenteric tubes in patients with perforation peritonitis. World J. Surg. 2005;29:1023-8.
|

Barlow R., Price P., Reid T.D., Hunt S., Clark G.W., Havard T.J., et al. Prospective multicentre randomised controlled trial of early enteral nutrition for patients undergoing major upper gastrointestinal surgical resection. Clin. Nutr. 2011;30:560-6.
|

Bakker O.J., van Brunschot S., van Santvoort H.C., Besselink M.G., Bollen T.L., Boermeester M.A., et al. Dutch pancreatitis study group early versus on-demand nasoenteric tube feeding in acute pancreatitis. N. Engl. J. Med. 2014;371:1983-93.
|

Lam N.N., Tien N.G., Khoa C.M. Early enteral feeding for burned patients–an effective method which should be encouraged in developing countries. Burns 2008;34:192-6.
|

Altintas N.D., Aydin K., Türkoðlu M.A., Abbasoðlu O., Topeli. Effect of enteral versus parenteral nutrition on outcome of medical patients requiring mechanical ventilation. Nutr. Clin. Pract. 2011;26:322-9.

Justo Meirelles C.M., de Aguilar-Nascimento JE. Enteral or parenteral nutrition in traumatic brain injury: a prospective randomized trial. Nutr Hosp 2011;26:1120-6.
|

Harvey S.E., Parrott F., Harrison D.A., Bear D.E., Segaran E., Beale R., et al. CALORIES Trial Investigators. Trial of the route of early nutritional support in critically ill adults. N. Engl. J. Med. 2014;371:1673-84.

Reignier J., Boisrame-Helms J., Brisard L., Lascarrou J.B., Ait Hssain A., Anguel N., et al. NUTRIREA-2 Trial Investigators; Clinical Research in Intensive Care and Sepsis (CRICS) group: .Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2). Lancet 2018;391:133-43.
|

Bozetti F., Braga M., Gianotti L., Gavazzi C., Mariani L. Postoperative enteral versus parenteral nutrition in malnourished patients with gastrointestinal cancer: a randomized multicentre trial. Lancet 2001;358:1487-92.
|

Gupta R., Patel K., Calder P.C., Yaqoob P., Primrose J.N., Johnson C.D. A randomised clinical trial to assess the effect of total enteral and total parenteral nutritional support on metabolic, inammatory and oxidative markers in patients with predicted severe acute pancreatitis (Apache II equal or = 6). Pancreatology 2003;3:406-13.
|

Eckerwall G.E., Axelsson J.B., Andersson R.G. Early nasogastric feeding in predicted severe acute pancreatitis: a clinical, randomized study. Ann Surg. 2006;244:959-65.
|

Petrov M.S., Kukosh M.V., Emelyanov N.V. A randomized controlled trial of enteral versus parenteral feeding in patients with predicted severe acute pancreatitis shows a signicant reduction in mortality and in infected pancreatic complications with total parenteral nutrition. Dig Surg 2006;23:336-45.
|

Sun J.K., Mu X.W., Li W.Q., Tong Z.H., Li J., Zheng S.Y. Effects of early enteral nutrition on immune function of severe acute pancreatitis patients. World J. Gastroenterol 2015;19:917-22.
|

Boelens P.G., Heesakkers F.F.B.M., Luyer M.D.P., van Barneveld K.W.Y., de Hingh I.H.J.T., Nieuwenhuijzen G.A.P., et al. Reduction of post operative ileus by early enteral nutrition in patients undergoing major rectal surgery: prospective, randomized, controlled study. Ann Surg. 2014;259:649-55.
|

Aiko S., Yoshizumi Y., Sugiura Y., Matsuyama T., Naito Y., Matsuzari J., et al. Benecial effects of immediate enteral nutrition after esophageal cancer surgery. Surg Today 2001;31:971-8.
|

Dhaliwal R., Cahill N., Lemieux M., Heyland D.K. The Canadian Critical Care nutrition guidelines in 2013: an update on current recommendations and implementation strategies. Nutr Clin Pract 2014;29:29-43.
|

Elke G., van Zanten A.R.H., Lemieux M., McCall M., Jeejeebhoy K.N., Kott M., et al. Enteral versus parenteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials. Crit. Care 2016;20:117.
|

MacLeod J.B., Lefton J., Houghton D., Roland C., Doherty J., Cohn S., et al. Prospective randomized control trial of intermittent versus continuous gastric feeds for critically ill trauma patients. J. Trauma 2007;63:57-61.
|

Serpa L.F., Kinura M., Faintuch J., Ceconello I. Effects of continuous versus bolus infusion of enteral nutrition in critical patients. Rev. Hosp. Clin. Fac. Med. Sao Paulo 2003;58:9-14.
|

Evans D.C., Forbes R., Jones C., Cotterman R., Njoku C., Thongrong C., et al. Continuous versus bolus tube feeds: does the modality affect glycemic variability or insulin requirements? J. Am. Coll. Surg. 2013;17:S57-8.

Rhoney D.H., Parker Jr. D., Formea C.M., Yap C., Coplin W.M. Tolerability of bolus versus continuous gastric feeding in brain-injured patients. Neurol Res 2002;24:613-20.
|

Tavares de Araujo V.M., Gomez P.C., Caporossi C. Enteral nutrition in critical patients; should the administration be continuous or intermittent? Nutr Hosp 2014;29:563-7.
|

Chowdhury A.H., Murray K., Hoad C.L., Costigan C., Marciani L., Macdonald I.A., et al. Effects of bolus and continuous nasogastric feeding on gastric emptying, small bowel water content, superior mesenteric artery blood ow, and plasma hormone concentrations in healthy adults: a randomized crossover study. Ann. Surg. 2016;263:450-7.

Argilera-Martinez R., Ramis-Ortega E., Carratala-Munuera C., Fernandez-Medina J.M., Saiz-Vinuesa D., Barrado-Narvion J. Effectiveness of continuous enteral nutrition versus intermittent enteral nutrition in intensive care patients: a systematic review. JBI Database Syst. Rev. Implement. Rep. 2014;12:281-317.

Evans D.C., Forbes R., Jones C., Cotterman R., Njoku C., Thongrong, et al. Continuous versus tube feeds: does modality affect glycemic variability, tube feeding volume, caloric intake or insulin utilization? Int J Crit Illness Inj Sci 2016;6:9-15.

Patel J.J., Rosenthal M.D., Heyland D.K. Intermittent versus continuous feeding in critically ill adults. Curr. Opin. Clin. Nutr. Metab. Care 2018;21: 116-20.
|

Kearns P.J., Chin D., Mueller L., Wallace K., Jensen W.A., Kirsch C.M. The incidence of ventilator-associated pneumonia and success in nutrient delivery with gastric versus small intestinal feeding: a randomized clinical trial. Crit. Care Med. 2000;28:1742-6.
|

Boivin M.A., Levy H. Gastric feeding with erythromycin is equivalent to transpyloric feeding in the critically ill. Crit. Care Med. 2001;29:1916-9.
|

Neumann D.A., DeLegge M.H. Gastric versus small-bowel tube feeding in the intensive care unit: a prospective comparison of efcacy. Crit. Care. Med. 2002;30:1436-8.

Davies A.R., Morrison S.S., Bailey M.J., Bellomo R., Cooper D.J., Doig G.S., et al. ENTERIC Study Investigators; ANZICS Clinical Trials Group. A multicenter, randomized controlled trial comparing early nasojejunal with nasogastric nutrition in critical illness. Crit Care Med 2012;40:2342-8.
|

Singh N., Sharma B., Sharma M., Sachdev V., Bhardwaj P., Mani K., et al. Evaluation of early enteral feeding through nasogastric and nasojejunal tube in severe acute pancreatitis: a noninferiority randomized controlled trial. Pancreas 2012;41:153-9.
|

Friedman G., Flávia Couto C.L., Becker M. Randomized study to compare nasojejunal with nasogastric nutrition in critically ill patients without prior evidence of altered gastric emptying. Indian J Crit Care Med 2015;19:71-5.
|

Wan B., Fu H., Yin J. Early jejunal feeding by bedside placement of a nasointestinal tube signicantly improves nutritional status and reduces complications in critically ill patients versus enteral nutrition by a nasogastric tube. Asia Pac. J. Clin. Nutr. 2015;24:51-7.

Huang H.H., Chang S.J., Hsu C.W., Chang T.M., Kang S.P., Liu M.Y. Severity of illness inuences the efcacy of enteral feeding route on clinical outcomes in patients with critical illness. J. Acad. Nutr. Diet. 2012;112:1138-46.

Acosta-Escribano J., Fernández-Vivas M., Grau Carmona T., Caturla-Such J., Garcia-Martinez M., Menendez-Mainer A., et al. Gastric versus transpyloric feeding in severe traumatic brain injury: a prospective, randomized trial. Intensive Care Med 2010;36:1532-9.
|

White H., Sosnowski K., Tran K., Reeves A., Jones M. A randomised controlled comparison of early post-pyloric versus early gastric feeding to meet nutritional targets in ventilated intensive care patients. Crit. Care. 2009;13:R187.
|

Davies A.R., Froomes P.R., French C.J., Bellomo R., Gutteridge G.A., Nyulasi I., et al. Randomized comparison of nasojejunal and nasogastric feeding in critically ill patients. Crit. Care. Med. 2002;30:586-90.
|

Montejo J.C., Grau T., Acosta J., Ruiz-Santana S., Planas M., García-De-Lorenzo A., et al. Nutritional and Metabolic Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units. Multicenter, prospective, randomized, single-blind study comparing the efcacy and gastrointestinal complications of early jejunal feeding with early gastric feeding in critically ill patients. Crit Care Med 2002;30:796-800.
|

Heyland D.K., Drover J.W., MacDonald S., Novak F., Lam M. Effect of postpyloric feeding on gastroesophageal regurgitation and pulmonary microaspiration: results of a randomized controlled trial. Crit. Care. Med. 2001;29:1495-501.
|

Day L., Stotts N.A., Frankfurt A., Stralovich-Romani A., Volz M., Muwaswes M., et al. A pilot study. J. Neurosci. Nurs. 2001;33(148-9): 155-9.
|

Esparza J., Boivin M.A., Hartshorne M.F., Levy H. Equal aspiration rates in gastrically and transpylorically fed critically ill patients. Intensive Care Med 2001;27:660-4.
|

Hsu C.W., Sun S.F., Lin S.L., Kang S.P., Chu K.A., Lin C.H., et al. Duodenal versus gastric feeding in medical intensive care unit patients: a prospective, randomized, clinical study. Crit. Care. Med. 2009;37:1866-72.
|

Alkhawaja S., Martin C., Butler R.J., Gwadry-Sridhar F. Post-pyloric versus gastric tube feeding for preventing pneumonia and improving nutritional outcomes in critically ill adults (review). Cochrane Database Syst. Rev. 2015;8:CD008875.
|

Deane A.M., Dhaliwal R., Day A.G., Ridley E.J., Davies A.R., Heyland D.K. Comparisons beween intragastric and small intestinal delivery of enteral nutrition in the critically ill: a systematic review and meta-analysis. Crit. Care. 2013;17:R125.
|

Alhazzani W., Almasoud A., Jaeschke R., Lo B.W., Sindi A., Altayyar S., et al. Small bowel feeding and risk of pneumonia in adult critically ill patients: a systematic review and meta-analysis of randomized trials. Crit Care 2013;17:R127.
|

Mahadeva S., Malik A., Hilmi I., Qua C.S., Wong C.H., Goh K.L. Difference in reux between duodenal and jejunal transnasal endoscopic placement of nasoenteric feeding tubes: outcomes and limitations in non-critically ill patients. Nutr. Clin. Pract. 2008;23:176-81.

Chapman M., Fraser R., Kluger K., Buist M., De Nichilo D. Erythromycin improves gastric emptying in critically ill patients intolerant of nasogastric feeding. Crit. Care Med. 2000;28:2334-7.
|

Nusal T., Erdogan B., Noyan T., Cekinmez M., Atalay B., Bilgin N. The effect of metoclopramide on gastric emptying in traumatic brain injury. J. Clin. Neurosci. 2007;14:344-8.
|

Yavagal D., Krnad D., Oak J. Metoclopramide for preventing pneumonia in critically ill patients receiving enteral tube feeding: a randomized controlled trial. Crit. Care. Med. 2000;28:1408-11.
|

Berne J., Norwood S., McAuley C., Vallina V.I., Villareal D., Waston J., et al. Erythromycin reduced delayed gastric emptying in critically ill trauma patients: a randomized, control trial. J. Trauma 2002;53:422-5.

Reignier J., Bensaid S., Perrin-Gachadoat D., Burdin M., Boiteau R., Tenaillon A. Erythromycin and early enteral nutrition in mechanically ventilated patients. Crit. Care. Med. 2002;30:1237-41.
|

Nassaj M., Ghorbani R., Frozeshfard M., Mesbahian F. Effect of metoclopramide on nosocomial pneumonia in patients with nasogastric. East. Mediterr. Health. J. 2010;16:371-4.
|

Ridley E.J., Davies A.R. Practicalities of nutrition support in the intensive care unit: the usefulness of gastric residual volume and prokinetic agents with enteral nutrition. Nutrition 2011;27:509-12.
|

Reigner J., Mercier E., Le Gouge A., Boulain T., Desachy A., Bellec E., et al. Effect of not monitoring residual gastric volume on risk of ventilator-associated pneumonia in adults receiving mechanical ventilation and early enteral feeding: a controlled randomized trial. JAMA 2013;209:249-56.
| |

Rhodes A., Evans L.E., Alhazzani W., Levy M.M., Antonelli M, Ferrer R, et al. Surviving sepsis initiative. Intensive Care Med 2017;43:304-77.
| |

Lewis K., Alqahtani Z., McIntyre L., Almenawer S., Alshamsi F., Rhodes A., et al. The efcacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials. Crit. Care. 2016;20:259.

Rogers G.B., Bruce K.D., Martin M.L., Burr L.D., Serisier D.J. The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic brosis bronchiectasis: an analysis from the randomised, double-blind, placebo-controlled BLESS trial. Lancet. Respir. Med. 2014;2:988-96.

Tappy L., Schwartz J.M., Schneiter P., Cayeux C., Revelly J.P., Fagerquist C.K.L. Effects of isoenergetic glucose-based or lipid based parenteral nutrition on glucose metabolism, de novo lipogenesis and respiratory gas exchanges in critically ill patients. Crit. Care. Med. 1998;26:860-7.
| |

Singh R., Cuervo A.M. Autophagy in the cell energetic balance. Cell. Metabol. 2011;13:495-504.
| |

Dvir D., Cohen J., Singer P. Computerized energy balance and complications in critically ill patients: an observational study. Clin. Nutr. 2005;25:37-44.
| |

Villet S., Chiolero R.L., Bollmann M.D., Revelly J.P., Cayeux R.N.M.C., Delarue J., et al. Negative impact of hypocaloric feeding and energy balance on clinical outcome in ICU patients. Clin. Nutr. 2005;24:502-9.
| |

Zusman O., Kagan I., Bendavid I., Theilla M., Cohen J., Singer P. Predictive equations predictive equations versus measured energy expenditure by indirect calorimetry: a retrospective validation. Clin. Nutr. 2018 (Article in Press).
| |

Frankeneld D.C., Coleman A., Alam S., Cooney R.N. Analysis of estimation methods for resting metabolic rate in critically ill adults. J. Parenter. Enteral. Nutr. 2009;33:27-36.
| |

Tatucu-Babet O.A., Ridley E.J., Tierney A.C.. The prevalence of under-prescription or over-prescription of energy needs in critically ill mechanically ventilated adults as determined by indirect calorimetry: a systematic literature review. J. Parenter. Enteral. Nutr. 2015;40:212-25.
| |

Graf S., Pichard C., Genton L., Oshima T., Heidegger C.P. Variability because body weight energy expenditure in mechanically ventilated patients: the weight of body weight! Clin. Nutr. 2017;36:224.
| |

Stapel S.N., de Grooth H.J., Alimohamed H., Elbers P.W., Girbes A.R., Weijs P.J., et al. Ventilator derived carbon dioxide production to assess energy expenditure in critically ill patients: proof of concept. Crit. Care. 2015;19:370.
| |

Oshima T., Graf S., Heiddeger C.P., Genton L., Pugin J., Pichard C. Can calculation of energy expenditure based on CO2 measurements replace indirect calorimetry? Crit. Care. 2017;21:13.
| |

Singer P., Anbar R., Cohen J., Shapiro H., Shalita-Chesner M., Lev S., et al. The tight calorie control study (TICACOS): a prospective, randomized, controlled pilot study of nutritional support in critically ill. Intensive Care Med 2011;37:601-9.
| |

Petros S., Horbach M., Seidel F., Weidhase L. Hypocaloric vs normocaloric nutrition in critically ill patients: a prospective randomized pilot trial. J. Parenter. Enteral. Nutr. 2014;40:242-9.
|

Heidegger C.P., Berger M.M., Graf S., Zing W., Darmon P., Costanza M.C., et al. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet 2013;381: 385-93.
|

Allingstrup M.J., Kondrup J., Wijs J., Claudius C., Pedersen U.G., Hein-Rasmussen R., et al. Early goal-directed nutrition versus standard of care in adult intensive care patients: the single centre, randomised, outcome assessor-blinded EAT-ICU trial. Intensive. Care Med. 2017;43:1637-47.
|

Weijs P., Looijaard W., Beishuizen A., Girbes A.R., Oudemans-van Staaten H.M. Early high protein intake is associated with low mortality and energy overfeeding with high mortality in non-septic mechanically ventilated critically ill patients. Crit. Care. 2014;18:701.
|

Zusman O., Theilla M., Cohen J., Kagan I., Bendavid I., Singer P. Resting energy expenditure, calorie and protein consumption in critically ill patients: a retrospective cohort study. Crit. Care. 2016;20:367.
|

Marik P.E., Hooper M.H. Normocaloric versus hypocaloric feeding on the outcomes of ICU patients: a systematic review and meta-analysis. Intensive Care. Med. 2016;42:316-23.
|

Iapachino G., Radrizzani D., Armani S., Noto A., Spanu P., Mistraletti G. Metabolic treatment of critically ill patients: energy balance and substrate disposal. Minerva Anesthesiol 2006;72:533-41.
|

Rice T.W., Morgan S., Hays M.A., Bernard G.R., Jensen G.L., Wheeler A.P. Randomized trial of initial trophic versus full-energy enteral nutrition in mechanically ventilated patients with acute respiratory failure. Crit. Care Med. 2011;39:967-74.
|

Arabi Y.M., Aldawood A.S., Haddad S.H., Al-Dorzi H.M., Tamim H.M., Jones G. Permissive underfeeding or standard enteral feeding in critically ill adults. N. Engl. J. Med. 2015;372:398-408.
|

Braunschweig C., Sheean P.M., Peterson S.J., Gomez Perez S., Freels S., Gurka D., et al. Intensive nutrition in acute lung injury: a clinical trial (intact). J. Parenter. Enteral. Nutr. 2015;39:13-20.
|

a National Heart, Lung and Blood institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Rice TW, Wheeler AP, Thompson BT, Steingrub J, Hite RD, et al. Initial trophic versus full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA 2012;307:795-803.
|

b Desachy A, Clavel M, Vuagnat A, Normand S, Gissot V, Francois B. Initial efcacy and tolerability of early enteral nutrition with immediate or gradual introduction in intubated patients. Intensive Care Med 2008;34:1054-9.
|

Charles E.J., Petroze R.T., Metzger R., Hranjec T., Rosenberger L.H., Riccio L.M., et al. Hypocaloric compared with eucaloric nutritional support and its effect on infection rates in a surgical intensive care unit: a randomized controlled trial. Am. J. Clin. Nutr. 2014;100:1337-43.
|

Rugules S.J., Rueda J.D., Diaz C.E., Rosselli D. Hyperproteic hypocaloric enteral nutrition in the critically ill patient: a randomized controlled clinical trial. Indian J. Crit. Care Med. 2013;17:343-9.
|

Rugeles S., Villarraga-Angula L.G., Ariza-Gutierrez A., Chaverra-Komerup S., Lasalvia P., Rosselli D. High-protein hypocaloric vs normocaloric enteral nutrition in critically ill patients: a randomized clinical trial. J. Crit. Care. 2016;35:110-4.
|

Peake S.L., Davies A.R., Deane A.M., Lange K., Moran J.L., O’Connor SN, et al. TARGET investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group: use of a concentrated enteral nutrition solution to increase calorie delivery to critically ill patients: a randomized, double-blind, clinical trial. Am. J. Clin. Nutr. 2014;100:616-25.
|

Wischmeyer P.E., Hasselmann M., Kummerlen C., Kozar R., Kutsogiannis D.J., Karvellas C.J., et al. A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial. Crit Care 2017;21:142.
|

Doig G., Simpson F., Heighes P.T., Bellomo R., Chesher D., Caterson I.D., et al. Refeeding Syndrome Trial Investigators Group: restricted versus continued standard caloric intake during the management of refeeding syndrome in critically ill adults: a randomised, parallel-group, multicentre, single-blind controlled trial. Lancet. Respir. Med. 2015;3:943-52.
|

Al-Dorzi H.M., Albarrak A., Ferwana M., Murad M.H., Arabi Y.M. Lower versus higher dose of enteral caloric intake in adult critically ill patients: a systematic review and meta-analysis. Crit. Care. 2016;20:358.
|

Parikh H.G., Miller A., Chapman M., Moran J.L., Peake S.L. Calorie delivery and clinical outcomes in the critically ill: a systematic review and meta-analysis. Crit. Care Resuscitation 2016;18:17-22.
|

Choi E.Y., Park D.A., Park J. Calorie intake of enteral nutrition and clinical outcomes in acutely critically ill patients: a meta-analysis of randomized controlled trials. J. Parenter. Enteral. Nutr. 2015;39:291-300.
|

Berger M.M., Pichard C. Understanding the causes of death in INTACT by Braunschweig et al. J. Parenter. Enteral. Nutr. 2015;39:144.
|

Heyland D.K., Cahill N., Day A.G. Optimal amount of calories for critically ill patients: depends on how you slice the cake. Crit. Care. Med .2011;39: 2619-26.
|

Bellomo R., Cass A., Cole L., Finfer S., Gallager M., Lee J., et al. Calorie intake and patient outcomes in severe acute kidney injury: ûndings from randomized evaluation of normal vs augmented level of replacement therapy (RENAL) study trial. Crit. Care. 2014;18:R45.
|

Casaer M.P. The nutritional energy to clinical outcome revisited. Crit Care 2014;18:140.
|

Crosara C.R., Melot C., Preiser J.C. U-shaped relationship between calorie intake and outcome in critically ill patients. Ann Intensive Care 2015;37:37.
|

Kutsogiannis J., Alberda C., Gramlich L., Cahill N.E., Wang M., Day A.G., et al. Observational study. Crit Care Med 2011;39:2691-9.
|

Bauer P., Charpentier C., Bouchet C., Nace L., Raffy F., Gaconnet N. Parenteral with enteral nutrition in the critically ill. Intensive Care Med 2000;26: 893-900.
|

Doig G.S., Simpson F., Sweetman E.A., Finfer S.R., Cooper D.J., Heighes P.T., et al. Early PN Investigators of the ANZICS Clinical Trials Group. Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a randomized controlled trial. JAMA 2013;309:2130-8.
|

Vincent J.L., Preiser J.L. Are prospective cohort studies an appropriate tool to answer clinical nutrition questions? Curr Opin Clin Nutr Metab Care 2013;16:182-6.
|

Hoffer L.J. Will we ever agree on protein requirements in the intensive care unit? Nutr Clin Pract 2017;32:94S-100S.
|

Hoffer L.J. Human protein and amino acid requirements. J Parenter Enteral Nutr 2016;40:460-74.
|

Ishibashi N., Plank L.D., Sando K., Hill G.L. Optimal protein requirements during the rst 2 weeks after the onset of critical illness. Crit Care Med 1998;26:1529-35.
|

Larson J., Ljljedahl S.O., Schildt B., Furst P., Vinnars E. Metabolic studies in multiple injured patients. Clinical features, routine chemical analysis and nitrogen balance. Acta Chir Scand 1981;147:317-24.
|

Shaw J.H., Wildbore M., Wolfe R.R. Whole body protein kinetics in severely septic patients. The response to glucose infusion and total parenteral nutrition. Ann Surg. 1987;205:288-94.
|

Leverve X., Guignier M., Carpentier F., Serre J.C., Caravel JP. Effect of parenteral nutrition on muscle amino acid output and 3-methylhistidine excretion in septic patients. Metabolism 1984;33:471-7.
|

Weijs P.J., Stapel S.N., de Groot S.D., Driessen R.H., Jong E., Girbes A.R.J., et al. Optimal protein and energy mortality in mechanically ventilated critically ill patients: a prospective observational cohort study. J. Parenter. Enteral. Nutr. 2012;36:60-8.
|

Allingstrup M.J., Esmailzadeh N., Wilkens Knudsen A., Espersen K., Hartvig Jensen T., Wis J., et al. Provision of protein and energy in relation to measured requirements in intensive care patients. Clin. Nutr. 2012;31:462-8.
|

Nicolo M., Heyland D.K., Chittams J., Sammarco T., Compher C. Clinical outcomes related to protein delivery in a critically ill population: a multicenter, multinational observation study. J. Parenter. Enteral. Nutr. 2016;40:45-51.
|

Compher C., Chittams J., Sammarco T., Nicolo M., Heyland D.K. Greater protein and energy intake may be associated with improved mortality in higher risk critically ill patients: a patient multicenter, multinational observational study. Crit. Care. Med. 2017;45:156-63.
|

Rooyakers O., Kouchek-Zadeh R., Tjader I., Norberg A., Klaude M., Wernerman J.L. Whole body protein turnover in critically ill patients with multiple organ failure. Clin. Nutr. 2015;34:95-100.
|

Song J.H., Lee H.S., Kim S.Y., Kim E.Y., Jung J.Y., Kang Y.A., et al. The inuence of protein provision in the early phase of intensive care on clinical outcomes for critically ill patients on mechanical ventilation. Asia Pac. J. Clin. Nutr. 2017;26:234-40.
|

Looijaard W.G., Dekker I.M., Stapel S.N., Girbes A.R., Twiks J.W., Oudemans-van Straaten H.M., et al. Skeletal muscle quality as assessed by CT-derived muscle density is associated with a 6 month mortality in mechanically ventilated patients. Crit. Care. 2016;20:386.
|

Doig G.S., Simpson F., Bellomo R., Heighes P.T., Sweetman E.A., Chesher D., et al. Intravenous amino acid therapy for kidney function in critically ill patients: a randomized controlled trial. Intensive Care Med 2015;41:1197-208.
|

Singer P. High-dose amino acid infusion preserves diuresis and improves nitrogen balance in non-oliguric acute renal failure. Wien Klin Wochenschr 2007;119:218-22.
|

Scheinkestel C.D., Kar L., Marshall K., Bailey M., Davies A., Nyulasi I., et al. Prospective randomized trial to assess caloric and protein needs of critically Ill, anuric, ventilated patients requiring continuous renal replacement therapy. Nutrition 2003;19:909-16.
|

Ferrie S., Allman-Farinelli M., Daley M., Smith K. Protein requirements in the critically ill: a randomized controlled trial using parenteral nutrition. J. Parenter. Enteral. Nutr. 2016;40:795-805.
|

Vanhorebeek I., Gunst J., Derde S., Derese I., Boussemaere M., Geiza F., et al. Insufcient activation of autophagy allows cellular damage to accumulate in critically ill patients. J. Clin. Endocrinol. Metab. 2011;96:E633-45.
|

Hermans G., Casaer M.C., Clerckx B., Guiza F., Venhullebusch T., Derde S., et al. Effect of tolerating macronutrient decit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial. Lancet. Respir. Med. 2013;1:621-9.
|

Casaer M.P., Wilmer A., Hermans G., Wouters P.J., Mesotten D., Van den Berghe G. Role of disease and macronutrient dose in the randomized controlled EPaNIC trial. A post hoc analysis. Am. J. Respir. Crit. Care. Med. 2013;187:247-55.
|

Zusman O., Bendavid .I, Kagan I., Theilla M., Cohen J., Singer P. Early administration of protein in critically ill patients: a large retrospective cohort study. Ann Intensive Care 2018. submitted for publication.
|

Koekkoek W.A.C.K., van Setten C.C.H., Olthof L.E., Kars J.C.N., van Zanten A.R.H.. Timing of PROTein INtake and clinical outcomes of adult critically ill patients on prolonged mechanical VENTilation: the PROTINVENT retrospective study. Clin Nutr 2018 (in press).
|

Burtin C., Clerckx B., Robbeets C., Ferdinande P., Langer D., Troosters T., et al. Early exercise in critically ill patients enhances short term functional recovery. Crit Care Med 2009;37:2499-505.
|

Schaller S.J., Anstey M., Blobner M., Edrich T., Graditz S.D., Gradwohl-Matis I., et al. Early, goal-directed mobilization in the surgical intensive care unit: a randomized controlled trial. Lancet 2016;388:1377-88.
|

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2019-06-19

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Singer, P., Blaser, A. R., Berger, M. M., Alhazzani, W., Calder, P. C., Casaer, M. P., Hiesmayr, M., Mayer, K., Montejo, J. C., Pichard, C., Preiser, J.-C., van Zanten, A. R., Oczkowski, S., Szczeklik, W., & Bischoff, S. C. (2019). Методичні рекомендації ESPEN щодо клінічного харчування у відділенні інтенсивної терапії. PAIN, ANAESTHESIA & INTENSIVE CARE, (2(87), 39–92. https://doi.org/10.25284/2519-2078.2(87).2019.171009

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