АД’ЮВАНТИ В РЕГІОНАРНІЙ АНЕСТЕЗІЇ

Автор(и)

  • У. А. Фесенко Львівський національний медичний університет імені Данила Галицького, Ukraine
  • В. С. Фесенко Львівський національний медичний університет імені Данила Галицького, Ukraine
  • І. А. Павленко Львівський національний медичний університет імені Данила Галицького, Ukraine
  • Р. М. Вербовський Львівський національний медичний університет імені Данила Галицького, Ukraine
  • О. В. Іванюшко Львівський національний медичний університет імені Данила Галицького, Ukraine

DOI:

https://doi.org/10.25284/2519-2078.2(95).2021.238295

Ключові слова:

ад’юванти, регіонарна анестезія, лікування болю

Анотація

В патофізіології болю беруть участь багато різних рецепторів, іонних каналів, які можуть слугувати мішенями для ад’ювантних препаратів. Незважаючи на появу місцевих анестетиків тривалої дії, покращення їх фармакокінетики, удосконалення техніки реґіонарного знеболювання, все це не повністю забезпечують потреби в лікуванні болю, особливо хронічного. Паралельно зі зростанням анестетичної сили місцевих анестетиків підвищується ризик їх системної токсичності. Усе це обґрунтовує застосування ад’ювантів в реґіонарній анестезії, що є цілком логічним з точки зору мультимодальної аналгезії. В статті наведений огляд сучасних літературних даних з питань застосування ад’ювантів в регіонарній анестезії. Описані механізми дії, дози, шляхи застосування ад’ювантних препаратів.

Посилання

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Опубліковано

2021-06-30

Як цитувати

Фесенко, У. А., Фесенко, В. С., Павленко, І. А., Вербовський, Р. М., & Іванюшко, О. В. (2021). АД’ЮВАНТИ В РЕГІОНАРНІЙ АНЕСТЕЗІЇ. PAIN, ANAESTHESIA & INTENSIVE CARE, (2(95), 17–24. https://doi.org/10.25284/2519-2078.2(95).2021.238295

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