Вибiр препаратiв для знеболювання у вагiтних

У. А. Фесенко


Проаналiзовано данi лiтератури щодо вибору препаратiв для знеболювання у вагiтних. Описано фiзiологiчнi змiни при вагiтностi, якi впливають на фармакокiнетику та фармакодинамiку лiкiв.

Ключові слова

анестезiя; аналгезiя; вагiтнiсть

Повний текст:



Pharmacology of pain. By ed. P. Beaulieu et al. (2010) Seattle. IASP Press. 622 p.

Datta S., Hurley R.J., Naulty J.S., et al. (1986) Plasma and cerebrospinal fluid progesterone concentrations in pregnant and nonpregnant women. Anesth Analg; 65: 950-4.

Kavaliers M., Wiebe J.P. (1987) Analgesic effects of the progesterone metabolite, 3α-hydroxy-5α-pregnan-20-one, and possible modes of action in mice. Brain Res; 415: 393-8.

Jayaram A., Carp H. (1993) Progesterone-mediated potentiation of spinal sufentanil in rats. Anesth Analg; 76: 745-50.

Palakniuk R.J., Shnider S.M., Eger E.L. (1974) Pregnancy decreases the requirement for inhaled anesthetic agents. Anesthesiology; 41: 82-3.

Gin T., Chan M.T.V. (1994) Decreased minimum alveolar concentration of isoflurane in pregnant humans. Anesthesiology; 81: 829-32.

Zhou H.H., Norman P., DeLima L.G. et al. (1995) The minimum alveolar concentration of isoflurane in patients undergoing bilateral tubal ligation in the postpartum period. Anesthesiology; 82: 1364-8.

Steinbrook R.A., Carr D.B., Datta S., et al. (1982) Dissociation of plasma and cerebrospinal fluid beta-endorphin-like immunoactivity levels during pregnancy and parturition. Anesth Analg; 61: 893-7.

Oyama J., Akitoma, Takeo T., et al. (1980) Beta endorphin in obstetric analgesia. Am J Obstet Gynecol; 137: 613-6.

Fagraeus L., Urban B., Bromage P. (1983) Spread of epidural analgesia in early pregnancy. Anesthesiology; 58: 184-6.

Hirabayashi Y., Shimizer R., Saitah K., et al. (1996) Acid-base state of cerebrospinal fluid during pregnancy and its effect on spinal anesthesia. Br J Anaesth; 77: 352-5.

Jayaram A., Singh P., Carp H. (1995) Sch 32615, an enkephalinase inhibitor, enhances pregnancy-induced analgesia in mice. Anesth Analg; 80: 944-8.

Dawson-Basoa M.E., Gintzler A.R. (1998) Gestational and ovarian sex steroid antinociception: synergy between spinal κ and δ opioid systems. Brain Res; 794: 61-67.

Lin N.J., Gintzler A.R. (1999) Gestational and ovarian sex steroid antinociception: relevance of uterine afferent and spinal α2-noradrenergic activity. Pain; 83: 359-68.

Briggs G.G., Freeman R.K., Yaffe S.J. (2008) Drugs in pregnancy and lactation. Baltimore: Williams & Wilkins.

Crawford J.S., Rudofsky S. (1965) The placental transmission of pethidine. Br J Anesth; 37: 929-33.

Kuhnert B.R., Kuhnert P.M., Tu A.S., et al. (1979) Meperidine and normeperidine levels following meperidine administration during labor. I. Mother. Am J ObstetI. Mother. Am J Obstet Gynecol; 133: 904-13.

Belsey E.M., Rosenblatt D.B., Lieberman B.A., et al. (1981) The influence of maternal analgesia on neonatal behaviour: I. Pethidine. Br J Obstet Gynecol; 88: 398-406.

Vertommen J.D., Vandermeulen E., Van Aken H., et al. (1991) The effects of the addition of sufentanil to 0.125% bupivacaine on the quality of analgesia during labor and on the incidence of instrumental deliveries. Anesthesiology; 74: 809-14.

Camann U.R., Denney R.A., Holby E.D., Datta S.A. (1992) A comparision of intratecal, epidural and intravenous sufentanil for labor analgesia. Anesthesiology; 77: 884-7.

Sibai B.M., Caritis S.N., Thom E., et al. (1993) Prevention of preeclampsia with low-dose aspirin in healthy, nulliparous pregnant women. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. N Engl J Med; 329: 1213-8.

Norton M.E., Merrill J., Cooper B.A.B., et al. (1993) Neonatal complications after the administration of indomethacin for preterm labor. N Engl J Med; 329: 1602-7.

Walker J.J., Johnstone J., Lloyd J. Rocha C.L. (1988) The transfer of ketorolac tromethamine from maternal to foetal blood. Eur J Clin Pharmacol; 34:509-11.

Wischnik A. (1989) The excretion of ketorolac tromethamine into breast milk after multiple oral dosing. Eur J Clin Pharmacol; 36:521-4.

Kirshon B., Moise K.J.Jr., Wasserstrum N. (1989) Effect of acetaminophen on fetal acid-base balance in chorioamnionitis. J Reprod Med; 34:955-9.

Зильбер А.П., Шифман Е.М. (1997) Акушерство глазами анестезиолога. Этюды критической медицины. Петрозаводск: Изд-во ПГУ, т. 3, 397 с.

Sprung J., Flick R.P., Wilder R.T. et al. (2009) Anesthesia for cesarean delivery and learning disabilities in a population-based birth cohort. Anesthesiology; 111(2): 302-10.

Head B.P., Patel H.H., Niesman I.R. et al. (2009) Inhibition of p75 neurotrophin receptor attenuates isofluran-mediated neuronal apoptosis in the neonatal central nervous system. Anesthesiology; 110, 4: 813-25.

Slikker W.J., Zou X.J., Hotchkiss C.E. et al. (2007) Ketamine-induced neuronal cell death in the perinatal rhesus monkey. Toxicol Sci; 98, 1: 145-58.

Brown E.N., Lydic R., Schiff N.D. (2010) General anesthesia, sleep, and coma. NEJM; 363:2638-50.

Пристатейна бібліографія ГОСТ

Creative Commons License
Ця робота ліцензована Creative Commons Attribution-NonCommercial 4.0 International License.

© Асоціація анестезіологів України, 1997-2017. ISSN 2520-226X (Online), ISSN 2519-2078 (Print).

Flag Counter